Vinux - Linux for Visually Impaired Users
Vinux is a remastered version of the Ubuntu Linux Distribution optimised for visually impaired users. It provides a screen-reader, full-screen magnification and support for Braille displays out of the box! It can be run from a Live CD without making any changes to your hard drive. If you like it you can install it to a USB pendrive or to your hard drive either alongside Windows using the Virtual Version, or as a complete replacement for windows.
http://vinuxproject.org/
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