Pyjs - Python Web Application Framework

Pyjs is a Rich Internet Application (RIA) Development Platform for both Web and Desktop. It contains a Python-to-Javascript compiler, an AJAX framework and a Widget Set API. Pyjs started life as a Python port of Google Web Toolkit (GWT), the Java-to-Javascript compiler. Additional to the web framework, they have Desktop version of Pyjs called Pyjs Desktop. It allows the same web application source code to be executed as a standalone desktop application instead of being stuck in a Web browser.